Forget expensive and proprietary MS Access. Forget about applications built on top of complex muiltitab spreadsheets. Drupal with Content Construction Kit, Views and Faceted Search are the right and way better solution for you.
Forget about building Flash-only web sites. Drupal and its modules is a better and semantically correct way for your Web 2.0 site.
Forget about PHP, ASP, JSP development from scratch. Drupal and its modules will put your site running faster with near zero programming.
This is a just a note for people building websites and general applications.